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Mouse anti-RANKL antibody delays oral wound healing and increases TRAP-positive mononuclear cells in bone marrow

OBJECTIVES: Denosumab, a human monoclonal antibody (mAb) that neutralizes receptor activator for nuclear factor κB ligand (RANKL), is associated with osteonecrosis of the jaw. However, the effect of denosumab on oral wounds is unclear. The aim was to determine the effect of anti-RANKL mAb on oral wo...

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Detalhes bibliográficos
Publicado no:Clin Oral Investig
Main Authors: Kuroshima, Shinichiro, Al-Salihi, Zeina, Yamashita, Junro
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4840226/
https://ncbi.nlm.nih.gov/pubmed/26254598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00784-015-1550-0
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