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Increased Numbers of Nonattached Osteoclasts After Long-Term Zoledronic Acid Therapy in Mice

Osteoclasts are key players in the maintenance of bone, which is an endocrine target and organ. Bisphosphonates, used for the management of metastatic bone diseases and osteoporosis, suppress osteoclasts. However, the impact of continuously suppressed osteoclasts is unknown. In this study, mice rece...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kuroshima, Shinichiro, Go, Virginia-Arlene A., Yamashita, Junro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249684/
https://ncbi.nlm.nih.gov/pubmed/22109892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1439
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