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Increased Numbers of Nonattached Osteoclasts After Long-Term Zoledronic Acid Therapy in Mice

Osteoclasts are key players in the maintenance of bone, which is an endocrine target and organ. Bisphosphonates, used for the management of metastatic bone diseases and osteoporosis, suppress osteoclasts. However, the impact of continuously suppressed osteoclasts is unknown. In this study, mice rece...

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Detalhes bibliográficos
Main Authors: Kuroshima, Shinichiro, Go, Virginia-Arlene A., Yamashita, Junro
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249684/
https://ncbi.nlm.nih.gov/pubmed/22109892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1439
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