High-resolution analysis of Zn(2+) coordination in the alkaline phosphatase superfamily by EXAFS and x-ray crystallography

Comparisons among evolutionarily related enzymes offer opportunities to reveal how structural differences produce different catalytic activities. Two structurally-related enzymes, E. coli alkaline phosphatase (AP) and X. axonopodis nucleotide pyrophosphatase/phosphodiesterase (NPP) have nearly ident...

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Bibliografski detalji
Glavni autori: Bobyr, Elena, Lassila, Jonathan K., Wiersma-Koch, Helen I., Fenn, Timothy D., Lee, Jason J., Nikolic-Hughes, Ivana, Hodgson, Keith O., Rees, Douglas C., Hedman, Britt, Herschlag, Daniel
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249517/
https://ncbi.nlm.nih.gov/pubmed/22056344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.10.040
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