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Arginine Coordination in Enzymatic Phosphoryl Transfer: Evaluation of the Effect of Arg166 Mutations in Escherichia coli Alkaline Phosphatase,

Arginine residues are commonly found in the active sites of enzymes catalyzing phosphoryl transfer reactions. Numerous site-directed mutagenesis experiments establish the importance of these residues for efficient catalysis, but their role in catalysis is not clear. To examine the role of arginine r...

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Detalhes bibliográficos
Main Authors: O'Brien, Patrick J., Lassila, Jonathan Kyle, Fenn, Timothy D., Zalatan, Jesse G., Herschlag, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587100/
https://ncbi.nlm.nih.gov/pubmed/18627128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800545n
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