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Alkaline Phosphatase Mono- and Di-esterase Reactions: Comparative Transition State Analysis

Enzyme-catalyzed phosphoryl transfer reactions have frequently been suggested to proceed through transition states that are altered from their solution counterparts. Previous work with E. coli alkaline phosphatase (AP), however, suggests that this enzyme catalyzes the hydrolysis of phosphate monoest...

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Hlavní autoři: Zalatan, Jesse G., Herschlag, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538955/
https://ncbi.nlm.nih.gov/pubmed/16433548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja056528r
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