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Alkaline Phosphatase Mono- and Di-esterase Reactions: Comparative Transition State Analysis

Enzyme-catalyzed phosphoryl transfer reactions have frequently been suggested to proceed through transition states that are altered from their solution counterparts. Previous work with E. coli alkaline phosphatase (AP), however, suggests that this enzyme catalyzes the hydrolysis of phosphate monoest...

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Detalhes bibliográficos
Main Authors: Zalatan, Jesse G., Herschlag, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538955/
https://ncbi.nlm.nih.gov/pubmed/16433548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja056528r
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