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Probing the Origins of Catalytic Discrimination between Phosphate and Sulfate Monoester Hydrolysis: Comparative Analysis of Alkaline Phosphatase and Protein Tyrosine Phosphatases
[Image: see text] Catalytic promiscuity, the ability of enzymes to catalyze multiple reactions, provides an opportunity to gain a deeper understanding of the origins of catalysis and substrate specificity. Alkaline phosphatase (AP) catalyzes both phosphate and sulfate monoester hydrolysis reactions...
Sparad:
| I publikationen: | Biochemistry |
|---|---|
| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American
Chemical Society
2014
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4222534/ https://ncbi.nlm.nih.gov/pubmed/25299936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500765p |
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