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Yeast-like chronological senescence in mammalian cells: phenomenon, mechanism and pharmacological suppression

In yeast, chronological senescence (CS) is defined as loss of viability in stationary culture. Although its relevance to the organismal aging remained unclear, yeast CS was one of the most fruitful models in aging research. Here we described a mammalian replica of yeast CS: loss of viability of over...

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Detalles Bibliográficos
Main Authors: Leontieva, Olga V., Blagosklonny, Mikhail V.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249453/
https://ncbi.nlm.nih.gov/pubmed/22156391
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