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A Cdk5-Dependent Switch Regulates Lis1/Ndel1/Dynein-Driven Organelle Transport in Adult Axons
Lissencephaly is a human developmental brain abnormality caused by LIS1 haploinsufficiency. This disorder is in large part attributed to altered mitosis and migration in the developing brain. LIS1 and an interacting protein, NDEL1, bind to cytoplasmic dynein, a microtubule motor protein. While the t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Society for Neuroscience
2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249231/ https://ncbi.nlm.nih.gov/pubmed/22114287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4108-11.2011 |
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