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Keratin 8 and 18 variants are associated with ethnic background and adverse outcome from acute liver failure
BACKGROUND & AIMS: Keratins 8 and 18 (K8/K18) provide anti-apoptotic functions upon liver injury. The cytoprotective function of keratins explains the over-representation of K8/K18 variants in patients with cirrhosis. However, K8/K18 variant-associated susceptibility to acute liver injury, which...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249217/ https://ncbi.nlm.nih.gov/pubmed/20538000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.06.007 |
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