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Increasing Rate of Cleavage at Boundary between Non-structural Proteins 4B and 5A Inhibits Replication of Hepatitis C Virus

In hepatitis C virus, non-structural proteins are cleaved from the viral polyprotein by viral encoded proteases. Although proteolytic processing goes to completion, the rate of cleavage differs between different boundaries, primarily due to the sequence at these positions. However, it is not known w...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Herod, Morgan R., Jones, Daniel M., McLauchlan, John, McCormick, Christopher J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249110/
https://ncbi.nlm.nih.gov/pubmed/22084249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311407
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