Genetic Complementation of Hepatitis C Virus Nonstructural Protein Functions Associated with Replication Exhibits Requirements That Differ from Those for Virion Assembly

Within the polyprotein encoded by hepatitis C virus (HCV), the minimum components required for viral RNA replication lie in the NS3-5B region, while virion assembly requires expression of all virus components. Here, we have employed complementation systems to examine the role that HCV polyprotein pr...

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Bibliographische Detailangaben
Hauptverfasser: Herod, Morgan R., Schregel, Vera, Hinds, Chris, Liu, Mengya, McLauchlan, John, McCormick, Christopher J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Genome Replication and Regulation of Viral Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958097/
https://ncbi.nlm.nih.gov/pubmed/24352463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03588-13
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