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Increasing Rate of Cleavage at Boundary between Non-structural Proteins 4B and 5A Inhibits Replication of Hepatitis C Virus
In hepatitis C virus, non-structural proteins are cleaved from the viral polyprotein by viral encoded proteases. Although proteolytic processing goes to completion, the rate of cleavage differs between different boundaries, primarily due to the sequence at these positions. However, it is not known w...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249110/ https://ncbi.nlm.nih.gov/pubmed/22084249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.311407 |
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