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A key cytochrome P450 hydroxylase in pradimicin biosynthesis
Pradimicins A-C (1–3) are a group of antifungal and antiviral polyketides from Actinomadura hibisca. The sugar moieties in pradimicins are required for their biological activities. Consequently, the 5-OH that is used for glycosylation plays a critical role in pradimicin biosynthesis. A cytochrome P4...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3248948/ https://ncbi.nlm.nih.gov/pubmed/22082563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.10.075 |
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