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Three enzymes involved in the N-methylation and incorporation of the pradimicin sugar moieties

Pradimicins are antifungal and antiviral natural products from Actinomadura hibisca P157-2. The sugar moieties play a critical role in the biological activities of these compounds. There are two glycosyltransferase genes in the pradimicin biosynthetic gene cluster, pdmS and pdmQ, which are putativel...

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Bibliografiske detaljer
Udgivet i:Bioorg Med Chem Lett
Main Authors: Napan, Kandy L., Zhang, Shuwei, Anderson, Thomas, Takemoto, Jon Y., Zhan, Jixun
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348331/
https://ncbi.nlm.nih.gov/pubmed/25677666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.01.043
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