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IκB kinase ε (IKKε) regulates the balance between type I and type II interferon responses

Virus infection induces the production of type I and type II interferons (IFN-I and IFN-II), cytokines that mediate the antiviral response. IFN-I (IFN-α and IFN-β) induces the assembly of IFN-stimulated gene factor 3 (ISGF3), a multimeric transcriptional activation complex composed of STAT1, STAT2,...

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Detalhes bibliográficos
Main Authors: Ng, Sze-Ling, Friedman, Brad A., Schmid, Sonja, Gertz, Jason, Myers, Richard M., tenOever, Benjamin R., Maniatis, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248534/
https://ncbi.nlm.nih.gov/pubmed/22171011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119137109
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