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Fascin1 suppresses RIG-I–like receptor signaling and interferon-β production by associating with IκB kinase ϵ (IKKϵ) in colon cancer
Fascin1 is an actin-bundling protein involved in cancer cell migration and has recently been shown also to have roles in virus-mediated immune cell responses. Because viral infection has been shown to activate immune cells and to induce interferon-β expression in human cancer cells, we evaluated the...
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| Gepubliceerd in: | J Biol Chem |
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| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5925820/ https://ncbi.nlm.nih.gov/pubmed/29496994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.819201 |
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