ASC Induces Apoptosis via Activation of Caspase-9 by Enhancing Gap Junction-Mediated Intercellular Communication

ASC (apoptosis-associated speck-like protein containing a CARD) is a key adaptor molecule of inflammasomes that mediates inflammatory and apoptotic signals. Aberrant methylation-induced silencing of ASC has been observed in a variety of cancer cells, thus implicating ASC in tumor suppression, althou...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Kitazawa, Masato, Hida, Shigeaki, Fujii, Chifumi, Taniguchi, Shun’ichiro, Ito, Kensuke, Matsumura, Tomio, Okada, Nagisa, Sakaizawa, Takashi, Kobayashi, Akira, Takeoka, Michiko, Miyagawa, Shin-ichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215782/
https://ncbi.nlm.nih.gov/pubmed/28056049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169340
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