Type I interferon response impairs differentiation potential of pluripotent stem cells

Upon virus infection, pluripotent stem cells neither induce nor respond to canonical type I interferons (IFN-I). To better understand this biology, we characterized induced pluripotent stem cells (iPSCs) as well as their differentiated parental or rederived counterparts. We confirmed that only iPSCs...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Eggenberger, Julie, Blanco-Melo, Daniel, Panis, Maryline, Brennand, Kristen J., tenOever, Benjamin R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2019
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347712/
https://ncbi.nlm.nih.gov/pubmed/30606801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812449116
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