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Prediction of Drug Combinations by Integrating Molecular and Pharmacological Data

Combinatorial therapy is a promising strategy for combating complex disorders due to improved efficacy and reduced side effects. However, screening new drug combinations exhaustively is impractical considering all possible combinations between drugs. Here, we present a novel computational approach t...

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Bibliografiske detaljer
Main Authors: Zhao, Xing-Ming, Iskar, Murat, Zeller, Georg, Kuhn, Michael, van Noort, Vera, Bork, Peer
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248384/
https://ncbi.nlm.nih.gov/pubmed/22219721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002323
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