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Prediction of Drug Combinations by Integrating Molecular and Pharmacological Data

Combinatorial therapy is a promising strategy for combating complex disorders due to improved efficacy and reduced side effects. However, screening new drug combinations exhaustively is impractical considering all possible combinations between drugs. Here, we present a novel computational approach t...

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Bibliografske podrobnosti
Main Authors: Zhao, Xing-Ming, Iskar, Murat, Zeller, Georg, Kuhn, Michael, van Noort, Vera, Bork, Peer
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248384/
https://ncbi.nlm.nih.gov/pubmed/22219721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002323
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