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Prediction of Drug Combinations by Integrating Molecular and Pharmacological Data

Combinatorial therapy is a promising strategy for combating complex disorders due to improved efficacy and reduced side effects. However, screening new drug combinations exhaustively is impractical considering all possible combinations between drugs. Here, we present a novel computational approach t...

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Detalhes bibliográficos
Main Authors: Zhao, Xing-Ming, Iskar, Murat, Zeller, Georg, Kuhn, Michael, van Noort, Vera, Bork, Peer
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248384/
https://ncbi.nlm.nih.gov/pubmed/22219721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002323
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