Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding

In pharmacology, it is crucial to understand the complex biological responses that drugs elicit in the human organism and how well they can be inferred from model organisms. We therefore identified a large set of drug-induced transcriptional modules from genome-wide microarray data of drug-treated h...

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Detalhes bibliográficos
Main Authors: Iskar, Murat, Zeller, Georg, Blattmann, Peter, Campillos, Monica, Kuhn, Michael, Kaminska, Katarzyna H, Runz, Heiko, Gavin, Anne-Claude, Pepperkok, Rainer, van Noort, Vera, Bork, Peer
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658274/
https://ncbi.nlm.nih.gov/pubmed/23632384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2013.20
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