Human adenovirus-specific T cells modulate HIV-specific T cell responses to an Ad5-vectored HIV-1 vaccine

Recombinant viruses hold promise as vectors for vaccines to prevent infectious diseases with significant global health impacts. One of their major limitations is that preexisting anti-vector neutralizing antibodies can reduce T cell responses to the insert antigens; however, the impact of vector-spe...

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Bibliografiske detaljer
Main Authors: Frahm, Nicole, DeCamp, Allan C., Friedrich, David P., Carter, Donald K., Defawe, Olivier D., Kublin, James G., Casimiro, Danilo R., Duerr, Ann, Robertson, Michael N., Buchbinder, Susan P., Huang, Yunda, Spies, Gregory A., Rosa, Stephen C. De, McElrath, M. Juliana
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248307/
https://ncbi.nlm.nih.gov/pubmed/22201684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60202
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