Llwytho...

Vaccine-induced HIV-specific CD8+ T cells utilize preferential HLA alleles and target specific regions of HIV-1

Most T cell-based HIV-1 vaccine candidates induce responses of limited breadth for reasons that are unclear. We evaluated vaccine-induced T-cell responses in individuals receiving an HIV-1 recombinant adenoviral vaccine. Certain HLA alleles (B27, B57, B35 and B14) are preferentially utilized to moun...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Friedrich, David, Jalbert, Emilie, Dinges, Warren L., Sidney, John, Sette, Alex, Huang, Yunda, McElrath, M. Juliana, Horton, Helen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196811/
https://ncbi.nlm.nih.gov/pubmed/21709567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e318228f992
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