Creatine kinase–mediated improvement of function in failing mouse hearts provides causal evidence the failing heart is energy starved

ATP is required for normal cardiac contractile function, and it has long been hypothesized that reduced energy delivery contributes to the contractile dysfunction of heart failure (HF). Despite experimental and clinical HF data showing reduced metabolism through cardiac creatine kinase (CK), the maj...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gupta, Ashish, Akki, Ashwin, Wang, Yibin, Leppo, Michelle K., Chacko, V.P., Foster, D. Brian, Caceres, Viviane, Shi, Sa, Kirk, Jonathan A., Su, Jason, Lai, Shenghan, Paolocci, Nazareno, Steenbergen, Charles, Gerstenblith, Gary, Weiss, Robert G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248286/
https://ncbi.nlm.nih.gov/pubmed/22201686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57426
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