Creatine Kinase-Overexpression Improves Myocardial Energetics, Contractile Dysfunction and Survival in Murine Doxorubicin Cardiotoxicity

Doxorubicin (DOX) is a commonly used life-saving antineoplastic agent that also causes dose-dependent cardiotoxicity. Because ATP is absolutely required to sustain normal cardiac contractile function and because impaired ATP synthesis through creatine kinase (CK), the primary myocardial energy reser...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gupta, Ashish, Rohlfsen, Cory, Leppo, Michelle K., Chacko, Vadappuram P., Wang, Yibin, Steenbergen, Charles, Weiss, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788056/
https://ncbi.nlm.nih.gov/pubmed/24098344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074675
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados