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Pancreatic GLP-1 receptor activation is sufficient for incretin control of glucose metabolism in mice

Glucagon-like peptide-1 (GLP-1) circulates at low levels and acts as an incretin hormone, potentiating glucose-dependent insulin secretion from islet β cells. GLP-1 also modulates gastric emptying and engages neural circuits in the portal region and CNS that contribute to GLP-1 receptor–dependent (G...

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Detalhes bibliográficos
Main Authors: Lamont, Benjamin J., Li, Yazhou, Kwan, Edwin, Brown, Theodore J., Gaisano, Herbert, Drucker, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248276/
https://ncbi.nlm.nih.gov/pubmed/22182839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42497
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