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Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors

The role of the gluco-incretin hormones GIP and GLP-1 in the control of β cell function was studied by analyzing mice with inactivation of each of these hormone receptor genes, or both. Our results demonstrate that glucose intolerance was additively increased during oral glucose absorption when both...

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Autori principali: Preitner, Frédéric, Ibberson, Mark, Franklin, Isobel, Binnert, Christophe, Pende, Mario, Gjinovci, Asllan, Hansotia, Tanya, Drucker, Daniel J., Wollheim, Claes, Burcelin, Rémy, Thorens, Bernard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC338268/
https://ncbi.nlm.nih.gov/pubmed/14966573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420518
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