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Gluco-Incretins Regulate Beta-Cell Glucose Competence by Epigenetic Silencing of Fxyd3 Expression

BACKGROUND/AIMS: Gluco-incretin hormones increase the glucose competence of pancreatic beta-cells by incompletely characterized mechanisms. METHODS: We searched for genes that were differentially expressed in islets from control and Glp1r(−/−); Gipr(−/−) (dKO) mice, which show reduced glucose compet...

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Bibliographische Detailangaben
Hauptverfasser: Vallois, David, Niederhäuser, Guy, Ibberson, Mark, Nagaray, Vini, Marselli, Lorella, Marchetti, Piero, Chatton, Jean-Yves, Thorens, Bernard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110016/
https://ncbi.nlm.nih.gov/pubmed/25058609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103277
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