Učitavanje...
Dual elimination of the glucagon and GLP-1 receptors in mice reveals plasticity in the incretin axis
Disordered glucagon secretion contributes to the symptoms of diabetes, and reduced glucagon action is known to improve glucose homeostasis. In mice, genetic deletion of the glucagon receptor (Gcgr) results in increased levels of the insulinotropic hormone glucagon-like peptide 1 (GLP-1), which may c...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3083792/ https://ncbi.nlm.nih.gov/pubmed/21540554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43615 |
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