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Activation of Enteroendocrine Membrane Progesterone Receptors Promotes Incretin Secretion and Improves Glucose Tolerance in Mice

Glucagon-like peptide-1 (GLP-1) secretion is classically regulated by ingested nutrients. To identify novel molecular targets controlling incretin secretion, we analyzed enteroendocrine cell pathways important for hormone biosynthesis and secretion. We demonstrate that progesterone increases GLP-1 s...

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Autors principals: Flock, Grace B., Cao, Xiemin, Maziarz, Marlena, Drucker, Daniel J.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526055/
https://ncbi.nlm.nih.gov/pubmed/22933106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0601
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