The direct Myc target Pim3 cooperates with other Pim kinases in supporting viability of Myc-induced B-cell lymphomas

The Pim kinases are weak oncogenes. However, when co-expressed with a strong oncogene, such as c-Myc, Pim kinases potentiate the oncogenic effect resulting in an acceleration of tumorigenesis. In this study we show that the least studied Pim kinase, Pim-3, is encoded by a gene directly regulated by...

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Библиографические подробности
Главные авторы: Forshell, Linus Plym, Li, Yongmei, Forshell, Tacha Zi Plym, Rudelius, Martina, Nilsson, Lisa, Keller, Ulrich, Nilsson, Jonas
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2011
Предметы:
Research Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248204/
https://ncbi.nlm.nih.gov/pubmed/21646687
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