Expression of FACT in mammalian tissues suggests its role in maintaining of undifferentiated state of cells

The Facilitates Chromatin Transcription (FACT) chromatin remodeling complex, comprised of two subunits, SSRP1 and SPT16, is involved in transcription, replication and DNA repair. We recently showed that curaxins, small molecules with anti-cancer activity, target FACT and kill tumor cells in a FACT-d...

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Hlavní autoři: Garcia, Henry, Fleyshman, Daria, Kolesnikova, Katerina, Safina, Alfiya, Commane, Mairead, Paszkiewicz, Geraldine, Omelian, Angela, Morrison, Carl, Gurova, Kateryna
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2011
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248156/
https://ncbi.nlm.nih.gov/pubmed/21998152
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