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Expression of FACT in mammalian tissues suggests its role in maintaining of undifferentiated state of cells

The Facilitates Chromatin Transcription (FACT) chromatin remodeling complex, comprised of two subunits, SSRP1 and SPT16, is involved in transcription, replication and DNA repair. We recently showed that curaxins, small molecules with anti-cancer activity, target FACT and kill tumor cells in a FACT-d...

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書誌詳細
主要な著者: Garcia, Henry, Fleyshman, Daria, Kolesnikova, Katerina, Safina, Alfiya, Commane, Mairead, Paszkiewicz, Geraldine, Omelian, Angela, Morrison, Carl, Gurova, Kateryna
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248156/
https://ncbi.nlm.nih.gov/pubmed/21998152
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