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Regulation of Autophagy by Neuropathological Protein TDP-43

TDP-43 is a DNA/RNA-binding protein with multicellular functions. As a pathosignature protein of a range of neurodegenerative diseases, TDP-43 is also the major component of the polyubiquitinated inclusions in the pathological cellular samples of these diseases. In normal cells, TDP-43 is processed...

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Hlavní autoři: Bose, Jayarama Krishnan, Huang, Chi-Chen, Shen, C.-K. James
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247982/
https://ncbi.nlm.nih.gov/pubmed/22052911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.237115
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