The Vinculin C-terminal Hairpin Mediates F-actin Bundle Formation, Focal Adhesion, and Cell Mechanical Properties

Vinculin is an essential and highly conserved cell adhesion protein, found at both focal adhesions and adherens junctions, where it couples integrins or cadherins to the actin cytoskeleton. Vinculin is involved in controlling cell shape, motility, and cell survival, and has more recently been shown...

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Autores principales: Shen, Kai, Tolbert, Caitlin E., Guilluy, Christophe, Swaminathan, Vinay S., Berginski, Matthew E., Burridge, Keith, Superfine, Richard, Campbell, Sharon L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Molecular Biophysics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247952/
https://ncbi.nlm.nih.gov/pubmed/22052910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.244293
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