The Vinculin C-terminal Hairpin Mediates F-actin Bundle Formation, Focal Adhesion, and Cell Mechanical Properties

Vinculin is an essential and highly conserved cell adhesion protein, found at both focal adhesions and adherens junctions, where it couples integrins or cadherins to the actin cytoskeleton. Vinculin is involved in controlling cell shape, motility, and cell survival, and has more recently been shown...

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Bibliographic Details
Main Authors: Shen, Kai, Tolbert, Caitlin E., Guilluy, Christophe, Swaminathan, Vinay S., Berginski, Matthew E., Burridge, Keith, Superfine, Richard, Campbell, Sharon L.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Molecular Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247952/
https://ncbi.nlm.nih.gov/pubmed/22052910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.244293
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