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Polyamidoamine (PAMAM) dendrimer conjugate specifically activates the A(3 )adenosine receptor to improve post-ischemic/reperfusion function in isolated mouse hearts
BACKGROUND: When stimulated by small molecular agonists, the A(3 )adenosine receptor (AR) mediates cardioprotective effects without inducing detrimental hemodynamic side effects. We have examined pharmacologically the protective properties of a multivalent dendrimeric conjugate of a nucleoside as a...
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Hoofdauteurs: | , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
BioMed Central
2011
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3247180/ https://ncbi.nlm.nih.gov/pubmed/22039965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-11-11 |
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