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Structural and biophysical determinants of αβ T-cell antigen recognition
The molecular rules that govern MHC restriction, and allow T-cells to differentiate between peptides derived from healthy cells and those from diseased cells, remain poorly understood. Here we provide an overview of the structural constraints that enable the T-cell receptor (TCR) to discriminate bet...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3246648/ https://ncbi.nlm.nih.gov/pubmed/22044041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03515.x |
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