Protein Kinase C Delta (PKCδ) Affects Proliferation of Insulin-Secreting Cells by Promoting Nuclear Extrusion of the Cell Cycle Inhibitor p21(Cip1/WAF1)

BACKGROUND: High fat diet-induced hyperglycemia and palmitate-stimulated apoptosis was prevented by specific inhibition of protein kinase C delta (PKCδ) in β-cells. To understand the role of PKCδ in more detail the impact of changes in PKCδ activity on proliferation and survival of insulin-secreting...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Ranta, Felicia, Leveringhaus, Johannes, Theilig, Dorothea, Schulz-Raffelt, Gabriele, Hennige, Anita M., Hildebrand, Dominic G., Handrick, René, Jendrossek, Verena, Bosch, Fatima, Schulze-Osthoff, Klaus, Häring, Hans-Ulrich, Ullrich, Susanne
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246440/
https://ncbi.nlm.nih.gov/pubmed/22216119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028828
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker