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A poly(ethylene glycol)-based surfactant for formulation of drug-loaded mucus penetrating particles
Mucosal surfaces are protected by a highly viscoelastic and adhesive mucus layer that traps most foreign particles, including conventional drug and gene carriers. Trapped particles are eliminated on the order of seconds to hours by mucus clearance mechanisms, precluding sustained and targeted drug a...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3246104/ https://ncbi.nlm.nih.gov/pubmed/21911015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.08.032 |
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