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Biodegradable mucus-penetrating nanoparticles composed of diblock copolymers of polyethylene glycol and poly(lactic-co-glycolic acid)

Mucus secretions coating entry points to the human body that are not covered by skin efficiently trap and clear conventional drug carriers, limiting controlled drug delivery at mucosal surfaces. To overcome this challenge, we recently engineered nanoparticles that readily penetrate a variety of huma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yu, Tao, Wang, Ying-Ying, Yang, Ming, Schneider, Craig, Zhong, Weixi, Pulicare, Sarah, Choi, Woo-Jin, Mert, Olcay, Fu, Jie, Lai, Samuel K., Hanes, Justin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818113/
https://ncbi.nlm.nih.gov/pubmed/24205449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-011-0048-9
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