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Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters

Crystallographic, computational and functional analyses of LeuT have revealed details of the molecular architecture of Na(+)-coupled transporters and the mechanistic nature of ion/substrate coupling, but the conformational changes that support a functional transport cycle have yet to be described fu...

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Detalhes bibliográficos
Main Authors: Claxton, Derek P., Quick, Matthias, Shi, Lei, de Carvalho, Fernanda Delmondes, Weinstein, Harel, Javitch, Jonathan A., Mchaourab, Hassane S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245867/
https://ncbi.nlm.nih.gov/pubmed/20562855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1854
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