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Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters
Crystallographic, computational and functional analyses of LeuT have revealed details of the molecular architecture of Na(+)-coupled transporters and the mechanistic nature of ion/substrate coupling, but the conformational changes that support a functional transport cycle have yet to be described fu...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3245867/ https://ncbi.nlm.nih.gov/pubmed/20562855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1854 |
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