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Correction of Microtubule-Kinetochore Attachment Errors: Mechanisms and Role in Tumor suppression

During mitosis, cells segregate duplicated chromosomes with high fidelity in order to maintain genome stability. Proper attachment of sister kinetochores to spindle microtubules is critical for accurate chromosome segregation and is driven by complex mechanisms that promote the capture of unattached...

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Bibliographic Details
Main Authors: Ricke, Robin M., van Deursen, Jan M.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245548/
https://ncbi.nlm.nih.gov/pubmed/21439393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2011.03.007
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