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Correction of Microtubule-Kinetochore Attachment Errors: Mechanisms and Role in Tumor suppression

During mitosis, cells segregate duplicated chromosomes with high fidelity in order to maintain genome stability. Proper attachment of sister kinetochores to spindle microtubules is critical for accurate chromosome segregation and is driven by complex mechanisms that promote the capture of unattached...

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Autors principals: Ricke, Robin M., van Deursen, Jan M.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245548/
https://ncbi.nlm.nih.gov/pubmed/21439393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2011.03.007
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