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Leukocyte ligands for endothelial selectins: specialized glycoconjugates that mediate rolling and signaling under flow

Reversible interactions of glycoconjugates on leukocytes with P- and E-selectin on endothelial cells mediate tethering and rolling of leukocytes in inflamed vascular beds, the first step in their recruitment to sites of injury. Although selectin ligands on hematopoietic precursors have been identifi...

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Autori principali: Zarbock, Alexander, Ley, Klaus, McEver, Rodger P., Hidalgo, Andrés
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245201/
https://ncbi.nlm.nih.gov/pubmed/22021370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-343566
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