P-selectin glycoprotein ligand-1–deficient mice have impaired leukocyte tethering to E-selectin under flow

P-selectin glycoprotein ligand-1 (PSGL-1) mediates rolling of leukocytes on P-selectin under flow. The glycoproteins that enable leukocyte tethering to or rolling on E-selectin are not known. We used gene targeting to prepare PSGL-1–deficient (PSGL-1(–/–)) mice, which were healthy but had moderately...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Xia, Lijun, Sperandio, Markus, Yago, Tadayuki, McDaniel, J. Michael, Cummings, Richard D., Pearson-White, Sonia, Ley, Klaus, McEver, Rodger P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2002
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC150926/
https://ncbi.nlm.nih.gov/pubmed/11927621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14151
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