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P-selectin glycoprotein ligand-1–deficient mice have impaired leukocyte tethering to E-selectin under flow
P-selectin glycoprotein ligand-1 (PSGL-1) mediates rolling of leukocytes on P-selectin under flow. The glycoproteins that enable leukocyte tethering to or rolling on E-selectin are not known. We used gene targeting to prepare PSGL-1–deficient (PSGL-1(–/–)) mice, which were healthy but had moderately...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC150926/ https://ncbi.nlm.nih.gov/pubmed/11927621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI14151 |
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