P-selectin glycoprotein ligand-1–deficient mice have impaired leukocyte tethering to E-selectin under flow
P-selectin glycoprotein ligand-1 (PSGL-1) mediates rolling of leukocytes on P-selectin under flow. The glycoproteins that enable leukocyte tethering to or rolling on E-selectin are not known. We used gene targeting to prepare PSGL-1–deficient (PSGL-1(–/–)) mice, which were healthy but had moderately...
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| Publicat a: | J Clin Invest |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC150926/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11927621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI14151 |
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