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Triphasic Force Dependence of E-Selectin/Ligand Dissociation Governs Cell Rolling under Flow

During inflammation, flowing leukocytes tether to and roll on vascular surfaces through the association and dissociation of selectin/ligand bonds. The interactions of P- and L- selectins with their respective ligands exhibit catch-slip bonds, such that increasing force initially prolongs and then sh...

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Detalles Bibliográficos
Main Authors: Wayman, Annica M., Chen, Wei, McEver, Rodger P., Zhu, Cheng
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920724/
https://ncbi.nlm.nih.gov/pubmed/20713000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.05.040
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