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Triphasic Force Dependence of E-Selectin/Ligand Dissociation Governs Cell Rolling under Flow
During inflammation, flowing leukocytes tether to and roll on vascular surfaces through the association and dissociation of selectin/ligand bonds. The interactions of P- and L- selectins with their respective ligands exhibit catch-slip bonds, such that increasing force initially prolongs and then sh...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920724/ https://ncbi.nlm.nih.gov/pubmed/20713000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.05.040 |
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