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Clustering endothelial E-selectin in clathrin-coated pits and lipid rafts enhances leukocyte adhesion under flow

During inflammation, E-selectin expressed on cytokine-activated endothelial cells mediates leukocyte rolling under flow. E-selectin undergoes endocytosis and may associate with lipid rafts. We asked whether distribution of E-selectin in membrane domains affects its functions. E-selectin was internal...

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Bibliographic Details
Main Authors: Setiadi, Hendra, McEver, Rodger P.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234047/
https://ncbi.nlm.nih.gov/pubmed/18029551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-113423
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